Flagyl (Metronidazole)

Flagyl (Metronidazole)

  • Flagyl (Metronidazole) Inhibits protein synthesis by breakage of DNA in the microorganism
  • Covers: Gram+, Gram-, MRSA, VRE & Anaerobe coverage
  • Does not cover the 3 P’s: No Pseudomonas, No Proteus, No Providencia
  • Hepatically cleared
  • Used for: anaerobic bacterial & protozoal infections, Trichomoniasis Bacterial Vaginosis abdominal infections, H.Pilori  and Clostridium Difficile infections
  • Flagyl can decrease the seizure threshold
  • Patient must not drink ETOH (will cause a Disulfiram Reaction)
  • Contraindicated in the 1st trimester of pregnancy and history of compromised hepatic dysfunction
  • Side effects: Disulfiram Reaction, metallic taste, GI upset, seizures, peripheral neuropathy, black hairy tongue & can increase the INR (interferes with Coumadin)
  • If allergic to Biaxin then you can substitute Flagyl for the treatment of H.Pilori 
  • Flagyl is also used in the treatment of STD’s